圖一 CAIA vs. CIA: (a)三角形：100%的小鼠在LPS注射后24-48小時(shí)即可見(jiàn)關(guān)節(jié)炎發(fā)作，在第5-7天病情達(dá)到高峰。（b）圓形：CIA誘發(fā)小鼠關(guān)節(jié)炎模型一般需要4周起病，即使使用CIA易感品系，如DBA/1J和B10.RIII小鼠。
表二 關(guān)節(jié)炎炎癥程度的臨床評(píng)分
得分
發(fā)病情況
0
Normal 正常
1
Mild, but definite redness and swelling of the ankle or wrist, or apparent redness and swelling limited to individual digits, regardless of the number of affected digits 輕度的、踝關(guān)節(jié)、腕關(guān)節(jié)發(fā)紅、腫脹
2
Moderate redness and swelling of ankle or wrist 踝關(guān)節(jié)或腕關(guān)節(jié)中度發(fā)紅腫脹
3
Severe redness and swelling of the entire paw including digits 爪子嚴(yán)重發(fā)紅、腫脹，包括指端
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