The OKT-3 monoclonal antibody reacts with human CD3ε, a 20 kDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. CD3ε is one of five polypeptide chains that combine to form the TCR complex. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays roles in TCR signaling, T lymphocyte activation, and antigen recognition. The OKT-3 antibody has immunosuppressive properties in vivo and has been shown to effectively treat renal, heart and liver allograft rejection.

產(chǎn)品名稱(chēng):InVivoMab anti-human CD3

反應(yīng)種屬:human

宿主來(lái)源:mouse

實(shí)驗(yàn)應(yīng)用:in vitro T cell stimulatioN/Activation, in vivo T cell depletion in humanized mice, ex vivo T cell inhibition for xenographs, Flow cytometry

同種型:IgG2a, κ

克隆性:Monoclonal

克隆號(hào):OKT-3

產(chǎn)品濃度:Lot specific,typically between 4-11 mg/ml

保存溫度:Undiluted at 4°C in the dark

運(yùn)輸溫度:Ship with adequate amount of blue ice to ensure the product remains at 4°C for the duration of transit

預(yù)期分子量:150 kDa

產(chǎn)品形式:液體

有效期:One year from the date of receipt if stored as recommended

產(chǎn)地:美國(guó)

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