應(yīng)用:Use as an adjuvant for the immunization of antigen in experimental animals.This incomplete Freund's Adjuvant (IFA) is suitable for collagen-induced arthritis (CIA) in rats and can also be used for booster injections of type II collagen to increase the incidence of CIA in mice.
1.Hu Y et al., Down-regulation of hypoxia-inducible factor-1α by RNA interference alleviates the development of collagen-induced arthritis in rats. Mol Ther Nucleic Acids 19:1330-1342, (2020). PMID: 32160704
2.Lee WS et al., MicroRNA-9 ameliorates destructive arthritis through down-regulation of NF-κB1-RANKL pathway in fibroblast-like synoviocytes. Clin Immunol 212:108348, (2020). PMID: 31978557