A lipid-soluble neurotoxin that acts as a sodium channel modulator. Binds with high affinity to the open state of the voltage-sensitive sodium channels at site 2, thereby causing a persistent ……
Y-27632 is a highly potent, cell permeable, selective and ATP competitive inhibitor of ROCK1 and ROCK2 (IC50=800nM). It acts as a potent inhibitor of agonist-induced Ca2+sensitization of myosin ……
Sphingosine-1-phosphate (1-SPP) is a putative second messenger that mobilizes calcium from intracellular stores via an IP3 independent pathway, activation of phospholipase D and stimulation of ……
Gentamycin-class aminoglycoside antibiotic. Cytotoxic to prokaryotic and eukaryotic cells. Induces apoptosis. Widely employed in the selection of eukaryotic expression vectors, in combination with ……
Y-27632 is a highly potent, cell permeable, selective and ATP competitive inhibitor of ROCK1 and ROCK2 (IC50=800nM). It acts as a potent inhibitor of agonist-induced Ca2+sensitization of myosin ……
Antibiotic. Induces apoptosis, which is not prevented by the presence of Bcl-2. Inhibits mitochondrial electron transport specifically between cytochromes b and c1.